We took a jellyfish, and did a bunch of studies to understand how it activates its muscles. We studied its propulsion and we made a map of where every single cell was. We used a software programme that we had developed a few years ago, borrowed from law enforcement agencies for doing quantitative analysis of fingerprints, and we used it to analyse the protein networks inside the cells.-- Kit Parker in an interview with Ed Yong. His team also hope to reverse-engineer other marine life forms. “We’ve got a whole tank of stuff in there, and an octopus on order.”
We found something very interesting right away: the electrical signals that the jellyfish uses to coordinate its pumping are exactly like that of the heart. In the heart, the action potential [electrical signal that travels along nerves – Ed] propagates as a wave through cardiac muscle. That’s how you get this nice, smooth contraction. The activation has to spread like when you drop a pebble in water. The same thing happens in the jellyfish, and I don’t think that’s by accident. My bet is that to get a muscular pump, the electrical activity has got to spread as a wavefront.
After we had the map of where every cell was, we took a rat apart and rebuilt it as a jellyfish.
23 July 2012
'We took apart a rat and rebuilt it as a jellyfish'
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